Osteoarthritis
What is osteoarthritis?
Osteoarthritis, also known as degenerative joint disease, or DJD, is the most common cause of knee pain in middle aged and older adults. Osteoarthritis is a disease which causes loss of the articular cartilage, the cartilage which lines the surface of the joints. The loss of cartilage can eventually result in changes in the bone and deformity.

Osteoarthritis and other knee damage.

How does osteoarthritis occur?
Most commonly, osteoarthritis occurs from no known cause. However, it can be a result of joint injuries or trauma, infections, or hereditary or developmental problems. How do I know I have osteoarthritis? Osteoarthritis most commonly leads to pain in the joint. The most common areas affected are the knees, hips, hands, shoulders and foot and ankle. When affecting the knee it can cause joint pain, stiffness, crepitation or cracking with motion, joint swelling or fluid, and deformity (bow-legged or knockkneed).

Do I need x-rays, a MRI or any other tests?
A set of x-rays is most commonly ordered to evaluate the knee for osteoarthritis. The lack of cartilage can be seen on the x-rays because there is decreased space between the bones. In addition, other changes to the bone which occur with osteoarthritis can be seen on a standard x-ray. Other causes of arthritis can be evaluated as well on a standard x-ray. A MRI is only occasionally necessary to rule out other suspected injuries to the knee.

Is there usually any other damage to the knee with Osteoarthritis?
In addition to affecting the joint surface (articular cartilage), the meniscus cartilage (the cartilage ring on the inside and the outside of the knee) can be torn as well. This usually occurs as part the disease process. Damage to the ligaments can occur as well, although this is usually not a significant problem.

What treatment options do I have?
The treatment options for osteoarthritis will depend on several factors, including your age, level of symptoms, and level of activity. There are a number of both non-surgical and surgical options, depending on the type and location of the arthritis. Each of the common non-surgical and surgical options for treatment will be described below.

NON-SURGICAL TREATMENTS FOR OSTEOARTHRITIS:

Will decreasing my activity help my osteoarthritis?
Weight bearing activities such as running or jogging can aggravate knees with significant arthritis. However, it is important to maintain a good range of motion and muscle strength in an arthritic joint. Non-impact activities such as biking and swimming can be especially beneficial.

Will losing weight help my arthritis?
Without question, weight loss decreases the level of stress in the weight bearing joints and can significantly reduce your pain. Therefore, weight loss to a healthy level is recommended in nearly all patients with osteoarthritis.

Are there medications I can take for my arthritis?
The most common medication used for osteoarthritis are nonsteriodal anti-inflammatory drugs (NSAIDs). This medication helps by both decreasing pain and inflammation in an arthritic joint. A variety of these medications are available and any one of them may be effective for your pain. For patients who get severe GI upset with medication, some newer agents called COX-2 inhibitors (Celebrex, Bextra) may decrease the likelihood of GI or ulcers when using these medications. You should always take these medications with food and discuss any other medications or drug allergies with your primary care physician.

What about taking Glucosamine and Chondroitin Sulfate?
The use of oral glucosamine and chondroitin sulfate have been shown in many studies to cause mild to moderate improvement in patient’s symptoms with osteoarthritis. For this reason, they can be beneficial for your pain. There are no studies available to demonstrate any long-term benefit from these medications in preventing future arthritis. There are many different formulations available over-the-counter at nutritional supply stores. The recommended dose of oral glucosamine and chondrointin sulfate is 1,500 mg of glucosamine and 1,200 mg of chondroitin sulfate daily.

What about a steroid injection?
Intraarticular steroids (cortisone) can provide significant short-term pain relief in patients with advanced arthritis. The inj ections commonly only last for a few weeks to three months. Occasionally, they can provide a longer benefit if the pain is due an acute episode of inflammation. Inj ections are generally limited to three or four a year, although there are no absolute guidelines.

Are there other types of injections I can receive?
There has been recent interest in intraarticular injections of hyaluronan in the knee (Synvisc and Hyalgan). These injections are an attempt to improve joint lubrication by providing some components found in normal joint fluid. These injections are given weekly, either three or five times. They have been shown to improve symptoms of osteoarthritis for up to six months. Overall, as with steroid injections, the improvements are short term.

Are there braces I can use?
For some patients with arthritis, a simple elastic sleeve does provide some relief and a feeling of stability to the knee. In addition, there are some braces designed to alter the joint mechanics when the arthritis is only in one particular area (unloader brace). These braces can be effective for particular types of arthritis.

SURGICAL TREATMENTS FOR OSTEOARTHRITIS

Is arthroscopy helpful for arthritis?
Arthroscopy for arthritis is helpful for certain symptoms, such as mechanical locking or catching. These can occur from a meniscus tear or loose body in the knee which can be removed arthroscopically. However, when arthroscopy is used to simply to “clean out” the joint and smooth articular cartilage, the results are unpredictable and short-lived. Only approximately 60% of patients report improvement after arthroscopy for arthritis, and a recent study showed no benefit of arthroscopy for arthritis over “sham” surgery.

Arthroscopic Care

What is an osteotomy (HTO, high tibial osteotomy)?
In patients who have arthritis on only the inside or the outside of the knee, and the rest of the knee is normal, an osteotomy is occasionally performed. This is generally performed in patients who are too young for total knee replacement. This procedure is performed to take the pressure off of the area of the knee with arthritis. A wedge of bone is generally added to the shinbone in order to realign the knee. Depending on the type of osteotomy, a bone graft from the hip may also be required to help the osteotomy heal. Sometimes, a wedge of bone is removed from the outside of the knee to perform the osteotomy. This procedure provides good pain relief for approximately 80% of patients up to 10 years.

Shape of a high tibial osteotomy

Wedge of bone removed, a plate is attached

Bone graft in osteotomy area.

What about cartilage replacement surgery?
There are new procedures available to replace small areas of missing cartilage. However, these procedures are currently only performed for patients with small areas of missing cartilage, and not more global arthritis. If only a small area of cartilage is affected, you may be a candidate for one of the procedures (See Patient Guide to Articular Cartilage Injuries or Patient Guide to Allograft Meniscus Transplantation).

What about the new Unispacer device?
The unispacer is a new metal device which is placed on the inner side of the knee when there is arthritis isolated to this area. This device acts as a metal spacer between the bones as an attempt to restore alignment to the leg. However, although there are surgeons around the country performing this procedure, there is not a single critical study that has looked at the results of this device. For this reason, it is difficult to recommend the procedure at this time.

What about joint arthroplasty (joint replacement)?
When arthritis is severe and the pain intolerable, the best procedure for a knee can be joint arthroplasty. Joint replacement is one of the best procedures available in orthopaedics for releaving pain and restoring function.

What is unicompartmental knee replacement?
Unicompartmental arthroplasty, or partial knee replacement, is used to replace only a portion of the knee. This is performed when the arthritis only affects one particular area of the knee, and the rest of the knee is normal. This is most commonly performed for arthritis on the inside of the knee. In partial knee replacement, the diseased portion is replaced with metal and plastic, but everything that’s normal is left alone. This can typically be performed through a small incision, and the recovery is shorter than a total knee replacement.

What is total knee replacement?
Total joint arthroplasty is when the entire knee is replaced. This involves placing a metal cap to the end of the thighbone and a plastic replacement to the tibia or shinbone. In addition, the kneecap may or may not be replaced with plastic. The results of total joint arthroplasty are excellent in most patients.

© Orthopaedic Specialists, Bryn Mawr, PA. May not be reproduced without the author’s permission. Images by MedImagery.net.